血小板生物能量学与老年女性的静息代谢率和运动能力有关
Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women
Keywords:platelets, resting metabolic rate (RMR), cardiopulmonary exercise testing (CPET), OXPHOS capacity, electron transfer capacity, inverted regression analysis
关键词:血小板, 静息代谢率 (RMR), 心肺运动试验 (CPET), OXPHOS 能力, 电子传递能力, 反向回归分析
作者:Heimler Stephanie R、Phang Howard J、Bergstrom Jaclyn、Mahapatra Gargi、Dozier Stephen、Gnaiger Erich、Molina Anthony JA
出版期刊:《Bioenerg Commun 2020.2 》(2020年)
Abstract:
This study investigates relationships between platelet mitochondrial bioenergetics and resting metabolic rate (RMR), body composition, and exercise fitness in older adult women. We report positive correlations between peak respiratory exchange ratio (RER) and RMR with five measures of platelet respiration, supporting the premise that blood cells can be utilized to report on mitochondrial function associated with physical health and fitness. Identifying mechanisms associated with physical performance among older adults supports the development of reliable biomarkers of healthy aging and can advance the development of efficacious interventions.
文章摘要:
本研究调查了老年女性血小板线粒体生物能量学与静息代谢率 (RMR)、身体成分和运动健康之间的关系。 我们报告了峰值呼吸交换率 (RER) 和 RMR 与血小板呼吸的五种测量值之间的正相关,支持血细胞可用于报告与身体健康和健康相关的线粒体功能的前提。 识别与老年人身体表现相关的机制,支持开发可靠的健康老龄化生物标志物,并可以促进有效干预措施的发展。
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